Preeclampsia impedes foetal kidney development by delivering placenta-derived exosomes to glomerular endothelial cells

Abstract Background Foetal renal dysplasia is still the main cause of adult renal disease.Placenta-derived exosomes are an important communication tool, and they may play an important role in placental (both foetal and maternal) function.We hypothesize that in women with preeclampsia, foetal renal dysplasia is impeded by delivering placenta-derived

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A novel method for rapid and reliable detection of complex vertebral malformation and bovine leukocyte adhesion deficiency in Holstein cattle

Abstract Background Complex vertebral malformation (CVM) and bovine leukocyte adhesion deficiency (BLAD) are two autosomal recessive lethal genetic defects frequently occurring in Holstein cattle, identifiable by single nucleotide polymorphisms.The objective of this study is to develop a rapid utopia hoodie brown and reliable genotyping assay to sc

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